Table 3.
Antibacterial activity of A. lasiantha extracts against pathogenic bacteria
| Extracts Codes | Diameter of growth zone inhibition Zone (mm ± SD at 100 μg/disc; MIC: μg/ml) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gram negative bacteria | Gram positive bacteria | |||||||||
| K. pneumoniae | MIC | M. luteus | MIC | E.coli | MIC | B. subtilis | MIC | S.aureus | MIC | |
| N | 7.9 ± 0.45 | > 100*** | 7 ± 0.97 | > 100*** | 8.6 ± 1.20 | > 100*** | 7.1 ± 0.62 | > 100*** | – | – |
| C | 7.7 ± 0.9 | > 100*** | 8 ± 0.43 | > 100*** | 8.3 ± 0.9 | > 100*** | 7.4 ± 1.04 | > 100*** | – | – |
| EA | 7.2 ± 0.61 | > 100*** | 9 ± 0.57 | > 100*** | 7.5 ± 0.78 | > 100*** | 7 ± 0.36 | > 100*** | – | – |
| A | – | – | – | – | 7.5 ± 0.54 | > 100*** | – | – | – | – |
| E | 7.1 ± 0.54 | > 100*** | 8 ± 0.68 | > 100*** | 7.1 ± 0.69 | > 100*** | – | – | – | – |
| M | 7.0 ± 0.82 | > 100*** | – | – | 8.5 ± 1.2 | > 100*** | – | – | – | – |
| W | – | – | – | – | – | – | – | – | – | |
| NEA | 8.5 ± 0.29 | > 100*** | 7 ± 0.43 | > 100*** | 7.1 ± 0.25 | > 100*** | – | – | – | – |
| EN | 7.3 ± 0.84 | > 100*** | 8 ± 0.53 | > 100*** | 7.3 ± 0.19 | > 100*** | – | – | – | – |
| MEC | 8.1 ± 0.32 | > 100*** | – | – | 7.1 ± 0.23 | > 100*** | – | – | – | – |
| MEEA | – | – | – | – | – | – | 9 ± 0.74 | 100*** | – | – |
| MEA | 8.3 ± 0.63 | > 100*** | – | – | – | – | – | – | – | – |
| AW | – | – | – | – | – | – | 11 ± 0.65 | 100*** | – | – |
| MD | – | – | – | – | – | – | – | – | – | – |
| PC | 12 ± 1.12 | 1.56 | 23 ± 1.04 | 0.78 | 28 ± 1.09 | 0.39 | 21 ± 0.9 | 3.12 | 14 ± 0.7 | 6.25 |
Results were presented as mean ± S.D. (n = 3). ***: P < 0.001. -- = No activity, PC: Positive Control (Cefixime), N: n-hexane, C: Chloroform, EA: Ethyl acetate, A: Acetone, E: Ethanol, M: Methanol, W: Distilled water, NEA: n-hexane-Ethyl acetate, EN: ethanol-n-hexane, MEC: methanol-chloroform MEEA: Methanol-Ethyl acetate, MEA: methanol-acetone, AW: acetone-water, MD: methanol-water