Table 2.
Performance characteristics
| RDT | HIV antibodies | Treponema pallidum antibodies | Final invalid rate (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | Inter-reader variability (%) | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | Inter-reader variability (%) | ||||||
| Initial | Final | Initial | Final | Initial | Final | Initial | Final | ||||
| SD Bioline HIV/Syphilis Duo | 100 (98.2–100) | 100 (98.2–100) | 99.5 (97.2–100) | 99.5 (97.2–100) | 0 | 86.5 (81.0–90.9) | 87.0 (81.5–91.3) | 99.5 (97.2–100) | 99.5 (97.2–100) | 4.0 | 0 |
| DPP HIV-Syphilis Assay | 100 (98.2–100) | 100 (98.2–100) | 96.0 (92.3–98.3) | 97.5 (94.3–99.2) | 1.0 | 85.0 (79.3–89.6) | 86.5 (81.0–90.9) | 100 (98.2–100) | 100 (98.2–100) | 4.5 | 0 |
| Multiplo Rapid TP/HIV Antibody Test | 99.5 (97.2–100) | 99.5 (97.2–100) | 99.5 (97.2–100) | 99.5 (97.2–100) | 0.3 | 70.0 (63.1–76.3) | 73.5 (66.8–79.5) | 99.0 (96.4–99.9) | 99.5 (97.2–100) | 4.8 | 0.5 |
| Insti Multiplex HIV-1/HIV-2/Syphilis Antibody Test | 99.5 (97.2–100) | 99.5 (97.2–100) | 88.0 (82.7–92.2) | 93.5 (89.1–96.5) | 4.5 | 78.5 (72.2–84.0) | 81.0 (74.9–86.2) | 99.0 (96.4–99.9) | 99.0 (96.4–99.9) | 1.8 | 0 |