Figure 1.
Pipeline for computing a person-based similarity index. (a) Creation of a structural profile (P) using regional measures (R) (e.g., cortical thickness or subcortical volumes) for each subject i. (b) Computation of Spearman’s correlation between each pair of individual profiles. The n profiles (P) are first converted to ranks (ρgi,… ρgn), cov(ρgi,ρgn): covariance of the rank variables (ρgi and ρgn), σ: standard deviation of the rank variables. (c) For subject i, the person-based similarity index (PBSI) is computed as the average of all pairwise correlations between the subject i and all other subjects.