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. 2018 Nov 13;27(1):17–28. doi: 10.1016/j.ymthe.2018.11.004

Figure 5.

Figure 5

Downstream Targets of miR-212/132

(A) Heatmap showing differentially regulated genes in the myocardium of AAV9-miR-212/132 with doxorubicin compared to AAV9-control with doxorubicin (n = 3). (B) Gene Ontology (GO) analysis of differentially regulated genes shows overrepresented biological process. (C) Expression levels of Rbfox1, Sgk3, Socs2, and Fitm2 in AAV9-control healthy hearts (n = 11), AAV9-control hearts with doxorubicin (n = 12), and AAV9-miR-212/132 hearts exposed to doxorubicin (n = 10). *p < 0.05; **p < 0.01. FC, fold change.