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. 2017 Apr 10;25(e2):e88–e92. doi: 10.1136/ejhpharm-2016-001170

Table 2.

The percentage of voriconazole remaining in elastomeric pumps stored at various temperatures and time intervals. Each sample was prepared in triplicate and analysed in triplicate. Results are presented as mean±SD

% initial concentration remaining
Time (hours) 4°C 25°C 35°C
0.9%
sodium chloride
5% Glucose 0.9% sodium chloride 5% Glucose 0.9% sodium chloride 5% Glucose
1 - - 98.7±0.4 99.6±0.3 98.6±0.1 99.1±0.8
2 - - 98.2±0.4 99.3±0.9 98.7±0.5 98.6±0.4
3 - - 98.3±0.0 98.8±0.5 98.2±0.5 97.6±0.2
4 - - 98.1±0.1 98.9±0.3 97.9±0.5 98.5±0.7
24 99.5±0.3 99.6±0.3 - - - -
48 98.9±1.0 99.4±0.2 - - - -
72 99.5±0.5 97.9±0.3 - - - -
96 98.1±0.2 97.2±0.1 - - - -