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. 2017 Aug 2;25(e2):e109–e114. doi: 10.1136/ejhpharm-2017-001205

Table 4.

Indicative amounts of PGE1 degradation product PGA1 over time in 10% dextrose injection solution stored in UPL and LS2 polypropylene syringes at 30°C

PGE1 concentration Time Percentage PGA1 detected
Syringe type
UPL LS2
Mean IC95% Mean IC95% p Value
1.5 µg/mL T0 1.8 (1.8 to 1.8) 2.0 (1.9 to 2.1) 0.03
24 hours 1.9 (1.9 to 1.9) 2.3 (2.2 to 2.4) 0.03
48 hours 2.0 (1.8 to 2.2) 2.5 (2.2 to 2.8) 0.03
72 hours 2.2 (2.1 to 2.3) 2.8 (2.5 to 3.1) 0.03
168 hours 2.9 (2.6 to 3.2) 3.9 (3.3 to 4.5) 0.03
15 µg/mL T0 1.8 (1.8 to 1.8) 1.9 (1.5 to 2.3) 0.46
24 hours 2.0 (1.9 to 2.1) 1.9 (1.5 to 2.3) 0.75
48 hours 2.2 (2.1 to 2.3) 2.1 (1.5 to 2.7) 0.75
72 hours 2.5 (2.4 to 2.6) 2.4 (1.9 to 2.9) 0.46
168 hours 3.7 (3.6 to 3.8) 3.5 (2.7 to 4.3) 0.46

LS, light-shielded; PGE1, prostaglandin E1; UPL, unprotected from light.