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. 2017 Jul 13;25(e2):e98–e101. doi: 10.1136/ejhpharm-2017-001281

Table 2.

Forced degradation studies

Stress condition % degradation Retention time of degraded products
Acid hydrolysis (1N HCl, 2 hours, 60°C) 95.2 1.44 min
Base hydrolysis (1N NaOH, 2 hours, 60°C) 23.5 1.31 min
Oxidative stress (3% H2O2, 2 hours, 60°C) 46.4 1.35 and 1.54 min
Thermal stress (60°C, 4 days) 10.0
Direct sunlight exposure (4 days) 0