Table 3.

pH determination at each day assay

Formulation	Mean±SD	pH (deviation between actual pH and initial pH)
	Day 0	Day 7	Day 14	Day 21	Day 30	Day 45	Day 60	Day 90
Powder 25°C 4°C	8.63±0.01	7.96 (−0.67) 8.50 (−0.13)	7.84 (−0.79) 8.43 (−0.20)	7.78 (−0.85) 8.36 (−0.27)	7.68 (−0.95) 8.09 (−0.54)	7.37 (−1.26) 7.91 (−0.72)	7.31 (−1.32) 7.86 (−0.77)	7.23 (−1.40) 7.76 (−0.87)
Tablets 25°C 4°C	8.12±0.01	7.73 (−0.39) 8.03 (−0.09)	7.56 (−0.56) 8.00 (−0.12)	7.49 (−0.63) 7.94 (−0.18)	7.37 (−0.75) 7.83 (−0.29)	7.18 (−0.94) 7.71 (−0.41)	7.09 (−1.03) 7.68 (−0.44)	6.96 (−1.16) 7.57 (−0.55)