Table 3.
Multivariable models for point-prevalence abstinence comparing varenicline with NRT users
| Multivariable-adjusted OR (95% CI) for abstinencea | |||
|---|---|---|---|
| 7-day | 1-month | 6-month | |
| Overall population | |||
| Varenicline | 1.21 (1.12, 1.32) | 1.24 (1.14, 1.34) | 1.11 (1.00, 1.24) |
| NRT patch or gum | 1 (reference) | 1 (reference) | 1 (reference) |
| p-value for medication × age | <0.05 | <0.05 | <0.05 |
| Age 25–54 years | |||
| Varenicline | 1.34 (1.22, 1.47) | 1.37 (1.24, 1.50) | 1.23 (1.09, 1.39) |
| NRT patch or gum | 1 (reference) | 1 (reference) | 1 (reference) |
| Age 55 years or older | |||
| Varenicline | 0.80 (0.67, 0.96) | 0.82 (0.69, 0.98) | 0.75 (0.60, 0.94) |
| NRT patch or gum | 1 (reference) | 1 (reference) | 1 (reference) |
NRT = nicotine replacement therapy; OR = odds ratios; CI = confidence interval.
a
Models adjusted for age (per 1-year change, the overall population only), sex, categorical education level, marital status, smoke-years (per 1-year change), nicotine dependency (light/moderate or severe), medical institution (community clinics or hospital outpatient clinics), categorical number of clinic visits, and categorical duration of medication received. The bold estimates were statistically significant at alpha level of 0.05.