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Loss of mitochondrial membrane potential (ΔΨM) in Ca9-22 and SAS cells treated with cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA). Oral cancer cells and fibroblasts were treated with HCUA and then harvested at 48 h post-treatment, stained with DiOC6(3), and then analyzed by flow cytometry (A). The relative changes in the percentage of low MMP cells in response to HCUA are shown (B). ***p<0.001 compared with mock cells.
