Table 4. Odds ratios for joint tenderness (at joint examination) per point increase in MRI-score in the wrist and MCP-joints, analyses done on joint level were stratified by ACPA-status.
| MRI-detected features | Univariable | Multivariable | ||
|---|---|---|---|---|
| OR (95%CI) | p-value | OR (95%CI) | p-value | |
| ACPA-positive | ||||
| Synovitis | 1.45 (0.71–2.96) | 0.31 | 0.83 (0.44–1.58) | 0.57 |
| BME | 2.47 (1.42–4.31) | 0.001 | 2.39 (1.31–4.36) | 0.005 |
| Tenosynovitis | 1.36 (1.01–1.83) | 0.041 | 1.22 (0.95–1.55) | 0.11 |
| Total inflammation score | 1.28 (1.06–1.54) | 0.010 | - | - |
| ACPA-negative | ||||
| Synovitis | 1.72 (1.33–2.21) | <0.001 | 1.96 (1.45–2.66) | <0.001 |
| BME | 0.97 (0.74–1.26) | 0.79 | 0.67 (0.50–0.90) | 0.008 |
| Tenosynovitis | 1.18 (1.02–1.36) | 0.026 | 1.06 (0.90–1.25) | 0.47 |
| Total inflammation score | 1.12 (1.03–1.21) | 0.006 | - | - |
Results of univariable and multivariable GEEs with joint tenderness as the outcome. All analyses are corrected for age and gender.
MRI, magnetic resonance imaging; MCP, metacarpophalangeal; OR, odds ratio; CI, confidence interval; ACPA, anticitrullinated protein antibody