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. 2018 Dec 20;28(2):382–402. doi: 10.1002/pro.3549

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A schematic representation of the mechanism of EGCG‐mediated modulation of γ‐Syn fibrillation pathway. The figure illustrates the mechanism of EGCG‐mediated modulation of γ‐Syn fibrillation pathway. The black arrows (→) represent γ‐Syn fibrillation pathway in the absence of EGCG, the black dashed arrows (→) represent EGCG modulated γ‐Syn fibrillation pathway and the red arrows () depict disaggregation pathway of γ‐Syn in the presence of EGCG. The cytotoxic effects of both EGCG untreated and treated γ‐Syn species are denoted by ++++ and +, for highly toxic and less toxic effects, respectively.

Inline graphic — A schematic representation of the mechanism of EGCG‐mediated modulation of γ‐Syn fibrillation pathway. The figure illustrates the mechanism of EGCG‐mediated modulation of γ‐Syn fibrillation pathway. The black arrows (→) represent γ‐Syn fibrillation pathway in the absence of EGCG, the black dashed arrows (→) represent EGCG modulated γ‐Syn fibrillation pathway and the red arrows () depict disaggregation pathway of γ‐Syn in the presence of EGCG. The cytotoxic effects of both EGCG untreated and treated γ‐Syn species are denoted by ++++ and +, for highly toxic and less toxic effects, respectively.