Table 2.

Overall diagnostic performance of ultrasound and MRI features for diagnosis of nodal metastases

Variables	Cut-off Value	AUC (95% CI)	p-value
Ultrasound (n = 316)
CTRa	>2.3 mm	0.635 (0.579 to 0.688)	<.001
CTDa	>2.3 mm	0.642 (0.586 to 0.694)	<.001
CT-bilateral differenceRb	>0.7 mm	0.656 (0.601 to 0.709)	<.001
CT-bilateral differenceDb	>0.7 mm	0.662 (0.607 to 0.714)	<.001
LD	≤13 mm	0.542 (0.486 to 0.598)	.234
SD	>4.5 mm	0.532 (0.475 to 0.588)	.380
LD/SD	≤1.7	0.557 (0.501 to 0.613)	.110
Eccentricity	N/A	0.565 (0.508 to 0.620)	.010
Fatty hilum loss	N/A	0.548 (0.491 to 0.604)	.003
Irregularity	N/A	0.512 (0.456 to 0.569)	.442
MRI (n = 260)
CTRa	>3.0 mm	0.622 (0.560 to 0.681)	.004
CTDa	>3.0 mm	0.632 (0.570 to 0.690)	.002
CT-bilateral differenceRb	>0.8 mm	0.647 (0.586 to 0.705)	<.001
CT-bilateral differenceDb	>0.8 mm	0.651 (0.589 to 0.708)	<.001
LD	>10 mm	0.560 (0.497 to 0.621)	.132
SD	>5.9 mm	0.588 (0.526 to 0.649)	.032
LD/SD	≤2.8	0.533 (0.470 to 0.595)	.412
Eccentricity	N/A	0.587 (0.525 to 0.648)	.003
Fatty hilum loss	N/A	0.532 (0.469 to 0.594)	.131
Irregularity	N/A	0.527 (0.465 to 0.589)	.171

AUC, area under the receiver operating characteristic curve; CT, cortical thickness; LD, long diameter; SD, short diameter.

^aIf the ALN had loss of fatty hilum, two CT features were assessed: radius (CT^R) or SD (CT^D).

^bCT-bilateral difference^R was calculated by CT^R minus CT of contralateral ALN and CT-bilateral difference^D by CT^D minus CT of contralateral ALN.