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. 2018 Jun 27;91(1092):20170930. doi: 10.1259/bjr.20170930

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© 2018 The Authors. Published by the British Institute of Radiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 Unported License http://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted non-commercial reuse, provided the original author and source are credited.

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Figure 3. — MRI post-gadolinium images of various grade IV GBM with hypermethylated and unmethylated MGMT. Imaging features showing: (a) mixed-nodular in a patient with hypermethylated MGMT and (b) ring enhancement in unmethylated MGMT. Another two cases demonstrating (c) preferential location of grade IV GBM with hypermethylation of the MGMT promoter located in parietal and occipital lobes, and (d) unmethylated of the MGMT promoter in the temporal lobes. GBM, glioblastoma multiformes; MGMT, O₆-methylguanine-DNA-methyltransferase.