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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Drug Target. 2018 Jan 9;26(5-6):420–434. doi: 10.1080/1061186X.2017.1419362

Figure 1.

Figure 1.

Nonlinear detection techniques of microbubbles. (A) Harmonic imaging. (B) Pulse inversion (PI). (C) Amplitude modulation (AM). Here is an example that the amplitude of the first transmitted pulse is twice the amplitude of the second transmitted pulse. (D) Contrast pulse sequence (CPS). Adapted from Caskey et al. [4] with permission, Copyright © 2011 Elsevier B.V.