Table 1.

Patient and Tumor Characteristics for All High-Grade Tumors and by Xenograft Success

	High Grade Only (n = 72)		Successful Xenografts Only (n = 32)		Unsuccessful Xenografts Only (n = 40)
Characteristic	No.	%	No.	%	No.	%
Sex
Female	34	47.2	16	50.0	18	45.0
Male	38	52.8	16	50.0	22	55.0
Grade
Low	0	0.0	0	0.0	0	0.0
High	72	100.0	32	100.0	40	100.0
Presentation
Primary	44	61.1	20	62.5	24	60.0
Recurrent or metastatic	28	38.9	12	37.5	16	40.0
Location
Abdomen/retroperitoneum	41	56.9	15	46.9	26	65.0
Extremity	31	43.1	17	53.1	14	35.0
Size, cm
< 10	48	66.7	22	68.8	26	65.0
> 10	24	33.3	10	31.3	14	35.0
Subtype
Leiomyosarcoma	15	20.8	8	25.0	7	17.5
Liposarcoma	13	18.1	8	25.0	5	12.5
NOS/spindle cell/UPS	15	20.8	7	21.9	8	20.0
Other	29	40.3	9	28.1	20	50.0
Neoadjuvant CT (any)
Yes	24	33.3	6	18.8	18	45.0
No	48	66.7	26	81.3	22	55.0
Neoadjuvant XRT (any)
Yes	11	15.3	0	0.0	11	27.5
No	61	84.7	32	100.0	29	72.5
Neoadjuvant therapy
None	42	58.3	26	81.3	16	40.0
CT alone	19	26.4	6	18.8	13	32.5
XRT alone	6	8.3	0	0.0	6	15.0
CT + XRT	5	6.9	0	0.0	5	12.5
Xenograftability
Success	32	44.4	32	100.0	0	0.0
Failure	40	55.6	0	0.0	40	100.0
Median age, years (range)	60.5 (16–91)		64.5 (16–91)		57 (0–89)
Median size, cm (range)	7.25 (0.9–35.5)		7.25 (1.5–23.8)		7.15 (0.9–35.5)
Median time to establish, days (range)	53.5 (9–184)		53.5 (9–184)		—

Abbreviations: CT, chemotherapy; NOS, not otherwise specified; UPS, undifferentiated pleomorphic sarcoma; XRT, radiation therapy.