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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Clin Cancer Res. 2018 Sep 27;24(23):6015–6027. doi: 10.1158/1078-0432.CCR-18-1013

Figure 4. Consensus mouse MAGE-A vaccine breaks tolerance to multiple MAGE-A isoforms in CD-1 outbred mice:

Figure 4

CD-1 outbred mice were immunized 3 times at 2 week intervals and sacrificed 1 week following final vaccination. Mice were immunized with 25μg of DNA followed by electroporation. (A,B) IFNγ ELISpot responses to consensus vaccine-matched peptides (A) or individual MAGE-A isoform matched peptides (B). 5 mice were used in the control group, and 15 mice were used in the consensus MAGE-A immunized group. Error bars indicate ± SEM.