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. Author manuscript; available in PMC: 2019 Jan 4.
Published in final edited form as: Transl Cancer Res. 2017 Jul;6(Suppl 5):S822–S839. doi: 10.21037/tcr.2017.05.22

Figure 1.

Figure 1

Schematics of direct and indirect effects of ionizing radiation and strategies for the therapeutic intervention. ROS, reactive oxygen species; PARP, poly (ADP-ribose) polymerase; IR, ionizing radiation; ATM, ataxia telangiectasia mutated.