Table 1.
r1 and r2 values under different magnetic fields
| Sample Nomenclature | H0 (T) a |
r1 (mM−1 s−1) (Fe+Gd) b |
r2 (mM−1 s−1) (Fe+Gd) b |
r2/r1 b |
r1 (mM−1 s−1) (Gd) c |
r2 (mM−1 s−1) (Gd) c |
r2/r1 c |
|---|---|---|---|---|---|---|---|
| FeGd-HN3 | 7.0 | 6.92±0.42 | 47.4±2.2 | 6.86±0.31 | 21.0±1.3 | 143.9±2.9 | 6.86±0.31 |
| 1.5 | 25.1±0.9 | 48.9±0.9 | 1.95±0.07 | 73.5±2.6 | 143.0±2.7 | 1.95±0.07 | |
| FeGd-HN3-RGD2 | 7.0 | 7.07 | 48.1 | 6.80 | 20.7 | 140.5 | 6.80 |
| 1.5 | 24.0 | 47.6 | 1.98 | 70.0 | 139.2 | 1.98 | |
| Magnevist® | 7.0 | 3.54 | 5.22 | 1.47 | 3.54 | 5.22 | 1.47 |
| 1.5 | 4.25±0.07 | 4.51±0.02 | 1.06±0.02 | 4.25±0.07 | 4.51±0.02 | 1.06±0.02 |
a
The r1 and r2 are measured on a MRI scanner system (7.0 T, Bruker, B-C 70/16 US), and a clinical MRI scanner system (1.5 T, Magnetom Avanto, Siemens, Germany)
b
Calculated according to the sum of Fe and Gd concentrations (mean ± SD, n = 3).
c
Calculated according to the Gd concentrations (mean ± SD, n = 3).