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. 2018 Oct 31;81(1):193–234. doi: 10.1007/s11538-018-0524-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 6 — High transmission region: Net increase in deaths due to long half-life IPT usage, or (Total child deaths due to sensitive and resistant strains of malaria with IPT) − (total child deaths without IPT) for 1 year, 5 years, and 10 years of IPT use for different levels of standard treatment effectiveness against the resistant strain, p. The results for the long half-life treatment drug are broken into deaths averted due to sensitive infection and additional deaths due to resistant infection. IPT treatment can reduce the number of child deaths due to the sensitive infection, but increase the number of child deaths due to the resistant strain for some scenarios (Colour figure online)