Fig. 8.

The effect of C. albicans cerebritis on mouse behavior. a–e After the intravenous injection of 25,000 viable cells of C. albicans into wild-type C57BL/6 mice, open-field tests were conducted on days 3 and 10 post fungal challenge to determine total distance traveled (a), average speed (b), inner zone entries (c), percent time in center (d), and percent distance in center (e). Mice were subsequently assessed in the T-maze spontaneous alternation task (f) and contextual fear conditioning (g). (n = 8, mean ± S.E.M, *p < 0.05, using one-way ANOVA followed by Dunnett’s test for multiple comparison). Data are shown as representative of two independent experiments