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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Expert Rev Proteomics. 2018 Sep 26;15(10):781–789. doi: 10.1080/14789450.2018.1525295

Table 1.

List of therapeutic and illicit drugs that have been analyzed by paper spray mass spectrometry.

Analyte Analyte Class Molecular Weight (Da) logP* LOD/LOQ (ng/mL) Reference
Acetaminophen Pharmaceutical 151.16 0.5 250 [15]
Amitriptyline Pharmaceutical 277.41 4.92 1 [6,7,15,16]
Amphetamine Illicit 135.21 1.76 1 [30]
Anabasine Pharmaceutical 308.37 3.57 0.1 [9]
Atenolol Pharmaceutical 266.34 0.57 50 [5]
Benzethonium Pharma 412.637 3.13 0.02 [15,20]
Benzoylecgonine Metabolite 289.33 1.71 1 [11]
Buprenorphine Illicit 467.64 4.98 1.6 [11]
Citalopram Pharmaceutical 324.39 3.5 0.1 [15,16]
Cocaine Illicit 303.12 2.3 0.05 [11,16]
Cotinine Metabolite 176.219 0.07 3,2,5 [9]
Cyclophosphamide Pharmaceutical 261 0.8 11 [8]
Cyclosporine Pharmaceutical 1202.63 3.64 5 [14]
Dextromorphan Pharmaceutical 271.4 3.6 0.6 [15]
Docetaxel Pharmaceutical 807.88 2.4 13 [8]
Heroin Illicit 369.41 1.58 125 [5,11]
Hydralazine Pharmaceutical 160.176 1 16 [9]
Ibuprofen Pharmaceutical 206.28 3.97 500 [15]
Imatinib Pharmaceutical 493.6 3 9 [2,8,39]
Irinotecan Pharmaceutical 586.67 3.2 13 [8]
Lidocaine Pharmaceutical 234.34 2.44 4 [16,17]
MDMA Illicit 193.24 1.65 0.04 [30]
Methamphetamine Illicit 149.23 2.07 0.3 [11,30]
Morphine Pharmaceutical/Illicit 285.34 0.89 12 [11,30]
Nicotine Toxic Alkaloid 162.23 1.17 1 [9]
Oxycodone Illicit 315.36 0.3 16 [11]
Paclitaxel Pharmaceutical 853.9 3 12,15 [8,15]
Pazopanib Pharmaceutical 437.52 3.59 0.5 [8]
Proguanil Pharmaceutical 253.73 2.53 0.08 [15]
Simvastatin Pharmaceutical 418.57 4.68 50 [15]
Sirolimus Pharmaceutical 914.19 4.3 0.5 [14]
Sitamaquine Pharmaceutical 343.51 5.11 5 [15]
Sunitinib Pharmaceutical 398.47 5.2 0.1 [20]
Tacrolimus Pharmaceutical 804.01 3.3 0.2 [18]
Tamoxifen Pharmaceutical 371.51 7.1 8 [8]
Telmisartan Pharmaceutical 514.62 7.7 0.3 [15]
THC Illicit 314.46 5.65 4 [30]
Topotecan Pharmaceutical 421.45 0.8 17 [8]
Verapamil Pharmaceutical 454.6 3.79 3, 0.75, 0.1 [1517]
*

LogP values were found from PubChem