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Significantly lower CD4 count in individuals harboring X4-using viruses in CRF01_AE cluster 4. (A) CD4 count for participants harboring phenotypically confirmed X4 or R5 viruses from the CYM cohort. (B) CD4 count comparison between participants harboring X4 or R5 viruses. The black line represents the mean CD4 count. The statistical difference was calculated using the two-tailed Mann–Whitney u test.
