Table 1.
List of genes and regions covered in the panel
| Gene | Target region | Hotspot position | No. of amplicons |
|---|---|---|---|
| AKT1 | Hotspot | E17 | 4 |
| AA23–59 | |||
| AA65–94 | |||
| BRAF | Hotspot | V600 | 1 |
| Her2 | Hotspot | S310 | 14 |
| AA428–438 | |||
| AA746–797 | |||
| AA832–986 | |||
| HRAS | Hotspot | AA3–35 (G12 and G13) | 3 |
| AA49–77 (Q61 and A66) | |||
| IDH2 | Hotspot | AA 132–162 | 1 |
| KRAS | Hotspot | G12 | 1 |
| SF3B1 | Hotspot | K700 | 1 |
| ESR1 | Part of exons | Exon 8–10 (LBD) | 10 |
| SMAD4 | Part of exons | Exon 8–12 | 10 |
| CDH1 | All exons | 46 | |
| CDKN1B | All exons | 9 | |
| FOXA1 | All exons | 18 | |
| GATA3 | All exons | 23 | |
| MAP2K4 | All exons | 22 | |
| MAP3K1 | All exons | 75 | |
| PIK3CA | All exons | 59 | |
| PIK3R1 | All exons | 11 | |
| PTEN | All exons | 24 | |
| RUNX1 | All exons | 24 | |
| TP53 | All exons | 21 |