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. 2018 Dec 19;24:9223–9231. doi: 10.12659/MSM.911695

Table 1.

Basic ultrasound (US) findings in study participants with thyroid nodules.

Characteristics Malignant Benign Total P-value
Gender 0.521
Female 17 (58.6%) 24 (51.1%) 41 (53.9%)
Male 12 (41.4%) 23 (48.9%) 35 (46.1%)
Age 51.69±11.99 48.34±13.84 49.62±13.19 0.285
Size (mm) 15.84±4.2 14.35±3.67 14.92±3.92 0.108
Depth (mm) 0.007*
Median 16.90 14.30 15.20
Interquartile range (IQR) 14.05–18.50 12.80–17.20 12.90–17.30
Shape 0.004*
Taller than wide 9 (31.0%) 3 (6.4%) 12 (15.8%)
Wider than tall 20 (69.0%) 44 (93.6%) 64 (84.2%)
Margin <0.001*
Well-defined 8 (27.6%) 36 (76.6%) 44 (57.9%)
Ill-defined 21 (72.4%) 11 (23.4%) 32 (42.1%)
Halo sign 0.111
Absent 25 (86.2%) 33 (70.2%) 58 (76.3%)
Present 4 (13.8%) 14 (29.8%) 18 (23.7%)
Echogenicity <0.001*
Markedly hypoechoic 17 (58.6%) 7 (14.9%) 24 (31.6%)
Hypoechoic 8 (27.6%) 22 (46.8%) 30 (39.5%)
Isoechoic 4 (13.8%) 10 (21.3%) 14 (18.4%)
Hyperechoic 0 (0.0%) 8 (17.0%) 8 (10.5%)
Posterior acoustic feature 0.278
Enhancement 2 (6.9%) 9 (19.1%) 11 (14.5%)
Shadowing 9 (31.0%) 10 (21.3%) 19 (25.0%)
None 18 (62.1%) 28 (59.6%) 46 (60.5%)
Composition 0.134
Solid 27 (93.1%) 36 (76.6%) 63 (82.9%)
Cystic portion 0–50% 2 (6.9%) 7 (14.9%) 9 (11.8%)
Cystic portion ≥50% 0 (0.0%) 4 (8.5%) 4 (5.3%)
Calcification 0.014*
Microcalcification 17 (58.6%) 12 (25.5%) 29 (38.2%)
Macrocalcification 4 (13.8%) 15 (31.9%) 19 (25.0%)
No 8 (27.6%) 20 (42.6%) 28 (36.8%)