Figure 1.

Generation and phenotype analysis of lepa KO zebrafish. (A) Schematic showing the TALEN left and right arm sequences used to target lepa gene on exon 2 in zebrafish. (B) Three-dimension model showing the predicted protein structure between wild type and lepa KO fish. (C) Comparison of body length and (D) body weight between wild type and lepa KO fish at six-month-old aged. (E) Appearance of wild type and lepa KO fish at six-month-old aged. (F) Morphometric analysis of wild type and lepa KO fish at six-month-old aged.