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. 2018 Dec 19;19(12):4118. doi: 10.3390/ijms19124118

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison of bone marrow aspirates and peripheral blood during episode of pancytopenic aplasia. (A): Whole peripheral blood (top) was compared to bone marrow aspirates (bottom row) with qualitative finding of reduced marrow cellular content. (B,C): CD4+/CD8+ CAR T cells, respectably, were detectable in the peripheral blood and to a minimal extent in the marrow. (D): Comparison of memory/activated T cell (CD45RO+), naïve T cell (CD45RA+), and CD27/28 co-expression in bone marrow (dark blue) and peripheral blood (light blue).