PDAC |
Pancreatic ductal adenocarcinoma |
NF-κB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
NEMO |
Regulatory subunit IKKγ |
EMT |
Epithelial-to-mesenchymal transition |
TNF-α |
Tumor necrosis factor alpha |
CAF |
cancer associated fibroblasts |
EGFR |
Epidermal growth factor receptor |
BRCA |
Breast cancer |
CDKN2A |
cyclin-dependent kinase Inhibitor 2A |
ATM |
Ataxia-Telangiectasia mutated |
STK |
Serine/threonine kinase |
PRSS |
serine protease |
MLH |
MutL homolog |
PALB2 |
Partner and localizer of BRCA2 |
TP53 |
Tumor protein p53 |
ARID1A |
AT-rich interactive domain-containing protein 1A |
MLL |
mixed-lineage leukemia protein |
TGFBR |
TGF-β receptor type |
Rel |
Reticuloendotheliosis |
IKK |
Inhibitor of κB kinase |
MAPKK |
Mitogen-activated protein kinase kinase kinase |
RANKL |
Receptor activator of nuclear factor kappa-Β ligand |
BAFF |
B-cell activating factor |
IL |
interleukin |
STAT |
Signal transducer and activator of transcription |
PI3K |
phosphoinositide 3-kinase |
NK |
Natural killer |
TRAIL |
TNF-related apoptosis-inducing ligand |
c-FLIP |
Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein |
BCL |
B-cell lymphoma |
BCL-XL |
B-cell lymphoma-extra large |
Puma |
p53 upregulated modulator of apoptosis |
CXCL |
chemokine (C-X-C motif) ligand |
SOCS |
Suppressor of cytokine signaling |
PTPN |
Tyrosine-protein phosphatase non-receptor type |
ADAM |
Disintegrin and metalloproteinase domain-containing protein |
MMP |
Matrix Metallopeptidase |
SFN |
Sulforaphane |
SMAD |
Single mothers against decapentaplegic |
US FDA |
United State food and drug administration |
ACCORD |
Action to Control Cardiovascular Risk in Diabetes |
FOLFIRINOX |
fluorouracil [5-FU], leucovorin, irinotecan, oxaliplatin |
TGF |
Transforming growth factor |
NIK |
NF-kappa-B-inducing kinase |
SQSMT1 |
sequestosome-1 |
SOX9 |
Sry-related HMG box 9 |
CDH2 |
Cadherin-2 |
SLUG |
SNAI2 |
TWIST |
Twist-related protein |
SNAIL-1 |
Snail Family Transcriptional Repressor 1 |
AP1 |
Activator protein 1 |
TNIP1 |
TNFAIP3-interacting protein 1 |
PPAR |
peroxisome proliferator-activated receptors |
PTEN |
Phosphatase and tensin homolog |
ROS |
Reactive oxygen species |
VEGF |
Vascular endothelial growth factor |
COX-2 |
Cyclooxygenase |
HIF1α |
Hypoxia-inducible factor 1-alpha |
GSK-3 |
Glycogen synthase kinase 3 |
Nrf-2 |
Nuclear respiratory factor 2 |