Table 4.

Diagnostic performance of miRNA pairs in urine supernatant and urine EVs.

Group Comparison	miRNA Pairs	AUC	Threshold	95% CI	Sensitivity%	Specificity%
h–c	miR-205.5p-miR-26b.5p	0.88	<−3.365	0.7212–1.039	30	100
	miR-107-miR-26b.5p	0.93	<−0.4896	0.8074–1.053	80	100
	miR-375-miR-26b.5p	0.83	<−0.6851	0.6293–1.037	70	100
	miR-151a.5p-miR-205.5p	0.84	>3.152	0.6506–1.029	30	100
	miR-29b.3p-miR-205.5p	0.88	>2.034	0.7278–1.032	50	100
	miR-29a.3p-miR-205.5p	0.83	> 3.344	0.6368–1.023	20	100
	miR-331.3p-miR-205.5p	0.79	>5.651	0.5624–1.015	10	100
h–b	miR-30a.5p-let-7g.5p	0.83	<−2.323	0.6107–1.056	33	100
b–c	miR-30c.5p-miR-30e.5p	0.83	>−0.7914	0.6351–1.032	20	100
	miR-103a.3p-miR-30c.5p	0.79	<1.153	0.5727–1.005	60	100
hm–cm	miR-20a.5p-miR-16.5p	0.85	<0.7185	0.6502–1.047	56	100
	miR-30b.5p-miR-16.5p	0.83	<−2.959	0.6355–1.021	22	100
	miR-31.5p-miR-16.5p	0.79	<1.833	0.5630–1.012	37.5	100
	miR-24.3p-miR-200b.3p	0.93	<1.307	0.8231–1.044	67	100
hm–bm	miR-31.5p-miR-200c.3p	0.83	<3.063	0.6356–1.031	60	100
	miR-31.5p-miR-16.5p	0.89	<2.256	0.7312–1.047	80	100
	miR-107-miR-141.3p	0.78	>5.213	0.5454–1.010	10	100
	miR-31.5p-miR-200b.3p	0.88	<3.104	0.7168–1.039	70	100
	miR-31.5p-miR-30e.3p	0.88	<1.252	0.7067–1.049	80	100
	miR-29a.3p-miR-30e.3p	0.84	<−0.1366	0.6625–1.026	40	100
	miR-31.5p-miR-660.5p	0.84	<0.5698	0.6630–1.026	70	100
	miR-29a.3p-miR-660.5p	0.86	<−0.7334	0.6679–1.043	20	100
	miR-20a.5p-miR-16.5p	0.73	<0.8182	0.4669–0.9931	70	100
	miR-107-miR-31.5p	0.87	>1.324	0.6716–1.062	10	100
bm–cm	miR-191.5p-miR-200a.3p	0.83	<2.595	0.6479–1.012	40	100
	miR-191.5p-miR-31.5p	0.91	<0.07563	0.7707–1.052	33	100
	let-7i.5p-let-7a.5p	0.83	<4.612	0.6117–1.039	57.14	100
	miR-100.5p-miR-200b.3p	0.81	<3.867	0.6002–1.022	55.56	100
	miR-106b.5p-miR-191.5p	0.88	>0.3940	0.7234–1.037	30	100