Figure 1.

Sex-specific activity of the secretory acid sphingomyelinase (S-ASM) in alcohol-dependent male and female patients during early abstinence and follow-up, compared to healthy control subjects. Boxplots show individual data, and the median and interquartile range. The numbers of male and female individuals are provided below the x-axis. p-values were calculated using the Mann–Whitney U test except for the pair-wise comparison for patients where the Wilcoxon signed-rank test was applied.