Table 3.
Mean extraction recovery and matrix effects of atractylenolides I, II, and III, atractyloside A, and acetaminophen in rat plasma.
| Compounds | Added C (ng/mL) | Extraction Recovery (%) | RSD (%) | Matrix Effects (%) | RSD (%) |
|---|---|---|---|---|---|
| Atractylenolide I | 5.6 | 87.81 ± 4.82 | 5.49 | 106.78 ± 0.85 | 0.80 |
| 28 | 91.79 ± 1.17 | 1.27 | 90.09 ± 12.27 | 13.62 | |
| 140 | 82.04 ± 2.1 | 2.64 | 73.40 ± 1.07 | 1.45 | |
| Atractylenolide II | 8 | 85.08 ± 5.30 | 6.23 | 99.48 ± 6.53 | 6.56 |
| 40 | 96.57 ± 6.99 | 7.24 | 86.80 ± 11 | 12.67 | |
| 200 | 97.93 ± 1.90 | 1.94 | 84.96 ± 0.31 | 0.36 | |
| Atractylenolide III | 8 | 85.76 ± 4.41 | 5.14 | 89.54 ± 9.79 | 10.93 |
| 40 | 92.79 ± 2.04 | 2.19 | 92.69 ± 9.39 | 10.13 | |
| 200 | 80.26 ± 4.42 | 5.50 | 69.25 ± 4.72 | 6.82 | |
| Atractyloside A | 6.88 | 82.47 ± 6.32 | 7.66 | 86.07 ± 6.49 | 7.54 |
| 17.2 | 86.17 ± 2.41 | 2.80 | 115.30 ± 2.67 | 2.31 | |
| 172 | 71.90 ± 4.97 | 6.92 | 120.28 ± 7.29 | 6.06 | |
| 4-Acetaminophen | 52 | 98.54 ± 6.81 | 6.91 | 112.39 ± 4.33 | 3.85 |