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Comparison of thermophilic and methophilic TrmB. (A) Sequence alignment of TrmB. Conserved regions are highlighted in three colored squares (red, green, blue). Asp133 is indicated by an asterisk. (B) Thermophilic and mesophilic TrmB proteins are illustrated schematically. The three colored regions correspond to the amino acid sequences in panel A. Thermophilic TrmB has a distinct long C-terminal region. Asp133 is highlighted with an arrow, and the red D corresponds to the Asp133.
