Table 1.

SOCE constituents and remodeling in different breast cancer cell subtypes.

Breast Cancer Subtype	Cell Line	SOCE Constituents	References
Estrogen receptor positive	MCF7	STIM1, STIM2, Orai3 and TRPC6	[50,53,82,83,84]
Triple Negative/Basal	MDA-MB-231	STIM1, Orai1 and TRPC6	[53,82,83,84]
Breast Cancer Subtype	Cell Line	SOCE Remodeling	References
Estrogen receptor positive	MCF7	↓STIM1, ↔STIM2, ↑Orai3 and ↑TRPC6	[50,53,82,83,84]
	HCC 1500	↔STIM1	[83]
	ZR751	↔STIM1	[83]
	T47D	↓STIM1	[83]
	BT474	↓STIM1	[83]
HER2	HCC1569	↑TRPC1	[85]
Triple Negative/Basal	MDA-MB-231	↔STIM1, ↑Orai1, ↑TRPC1 and ↑TRPC6	[53,82,83,84,86]
	MDA-MB-468	↑TRPC1	[86]
	BT20	↑STIM1	[83]
	HCC 1937	↔STIM1	[83]
	Patients	↑STIM1, ↓STIM2 and ↑TRPC6	[49]

↔ Similar levels in cancer and non-tumoral cells. ↑ Increased levels in cancer cells. ↓ Decreased levels in cancer cells.