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. 2018 Nov 28;19(12):3782. doi: 10.3390/ijms19123782

Figure 6.

Figure 6

Effects of BDNF and delivery vehicle on astrogliosis following dMCAo. Hydrogel + BDNFHIGH treatment reduces GFAP IR in the ipsilateral (A) corpus striatum and (B) anterior motor cortex. Representative photomicrographs of GFAP (Cy5, mapped to yellow) and DAPI nuclear stain (blue) at 20× magnification from each treatment group and ROI are shown below. Vehicle (n = 5), BDNF-only (n = 5), hydrogel-only (n = 5), hydrogel + BDNFLOW (n = 5), and hydrogel + BDNFHIGH (n = 5). Scale bar = 20 µm. IR = immunoreactivity. Error bars indicate the mean ± SEM; * p < 0.05, *** p < 0.001.