Table 1.
Qualitative and quantitative composition (%, w/w) for emulsions: with and without ferulic acid and/or each ionic liquid (IL); with and without rutin and/or each IL. O/W: oil-in-water.
Drug | Composition | O/W Emulsions | ||
---|---|---|---|---|
Control | [Cho][Phe] | [Cho][Glu] | ||
Ferulic Acid | Crodafos® CES | 4 or 6 | 4 | 6 |
Isopropyl myristate | 2 | 2 | 2 | |
Butylated hydroxytoluene (BHT) | 0.1 | 0.1 | 0.1 | |
Ethylenediaminetetraacetic acid disodium dihydrate (EDTA Na2) | 0.1 | 0.1 | 0.1 | |
Propylene glycol (PG) | 5 | 5 | 5 | |
Polyethylene glycol (PEG 400) | 5 | 5 | 5 | |
Parabens solution | 1 | 1 | 1 | |
Ferulic acid | – | 0.13 | 0.12 | |
IL | – | 0.2 | 0.2 | |
Triethanolamine | q.s. to pH = 5 q.s. to 100 |
|||
Deionized water | ||||
Rutin | Crodafos® CES | 4 or 6 | 4 | 6 |
Isopropyl myristate | 2 | 2 | 2 | |
Butylated hydroxytoluene (BHT) | 0.1 | 0.1 | 0.1 | |
Ethylenediaminetetraacetic acid disodium dihydrate (EDTA Na2) | 0.1 | 0.1 | 0.1 | |
Propylene glycol (PG) | 5 | 5 | 5 | |
Polyethylene glycol (PEG 400) | 5 | 5 | 5 | |
Parabens solution | 1 | 1 | 1 | |
Rutin | – | 0.115 | 0.068 | |
IL | – | 0.2 | 0.2 | |
Triethanolamine | q.s. to pH = 5 q.s. to 100 |
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Deionized water |