Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cytotoxicity towards human HCT-15 cancer cell spheroids.
| IC50 (µM) ± SD | |||
|---|---|---|---|
| 1 | CDDP | OXP | |
| HCT-15 | 40.4 ± 5.1 | 71.1 ± 3.9 | 33.2 ± 4.6 |
Spheroids (3 × 103 cells/well) were treated for 72 h with tested compounds and the growth inhibitory activity was assessed using APH assay. IC50 values were calculated from the dose-survival curves using the four-parameter logistic model (p < 0.05). SD = standard deviation.
