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. 2018 Nov 22;19(12):3709. doi: 10.3390/ijms19123709

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Principal Component Analysis performed on raw amino acid composition (A) and amino acids encoding into groups (B) for SPs and mature proteins from Plasmodiidae and other organisms. SPs from Plasmodiidae create a set, which is quite distinct from other SPs according to raw amino acid composition. However, the application of amino acid encoding chosen in cross-validation makes these sets similar but still supporting a significant difference between SPs and mature proteins. Concentration ellipses cover 95% of points from a given set.