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. 2018 Dec 14;23(12):3315. doi: 10.3390/molecules23123315

Figure 1.

Figure 1

Chemical structure and cytotoxicity of chenodeoxycholic acid (CDCA). (A) Chemical structure of CDCA. (B) Cytotoxicity of CDCA on A549 cells. (C) Cytotoxicity of CDCA on MDCK cells. Confluent A549 or MDCK cells were treated with different concentrations of CDCA. After 48 h or 72 h, cell viability was measured by 3-(4,5-dimethylthiozol-2-yl)-3,5-dipheryl tetrazolium bromide (MTT) assay. The results are expressed as percentage (%) of mock treated cells (represented with PBS). Values represent the mean (%) ± SD from 3 independent determinations. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared to the PBS control.