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. 2018 Nov 27;23(12):3088. doi: 10.3390/molecules23123088

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — Reagents and conditions: (i) pyridinium bromide perbromide, CH₂Cl₂, pyridine, 0 °C, 40 min; (ii) N-(2,6-dimethyl-phenyl)-2-piperazin-1-ylacetamide, K₂CO₃, THF/DMF, room temperature, overnight.