Table 1.
Enzyme | Activity Level | Class | kcat | kcat/Km | KI (Acetazolamide) | Ref |
---|---|---|---|---|---|---|
(s−1) | (M−1 s−1) | (nM) | ||||
hCA I | moderate | α | 2.0 × 105 | 5.0 × 107 | 250 | [12] |
hCA II | very high | α | 1.4 × 106 | 1.5 × 108 | 12 | [12] |
mtCA 1 | moderate | β | 3.9 × 105 | 3.7 × 107 | 480 | [32] |
mtCA 2 | high | β | 9.6 × 105 | 9.3 × 107 | 9.8 | [32] |
EhiCA | high | β | 6.7 × 105 | 8.9 × 107 | 509 | this work |