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. 2018 Nov 23;19(12):3727. doi: 10.3390/ijms19123727

Table 2.

Association of circulating irisin with physical activity and exercise training and dietetic interventions.

Author Sample Intervention Correlation Results
Jang 2017 [8] n = 618 (316 boys) Korea 12–15 y-o. NW (n = 370), OB (n = 248) No Intervention + In NW girls
+ In NW active
Elizondo-Montemayor 2017 [4] n = 40 (20 boys) Mexico 6–12 y-o. UW (n = 5), NW (n = 5), OW (n = 5), OB (n = 5). Reported aerobic exercise (days per week and hours per day) With days per week
- With hours per day
Löffler 2015 [11] n = 29 (11 boys) Germany 8–21 y-o. OB (n = 10 (2 boys)). 15-min maximum cycle ergometer + In all subjects
n = 58 OB (23 boys) Germany 7–17 y-o. 4–6 weeks of nutritional and aerobic training +/− In boys
n = 88 Germany 11–12 y-o. CO [n = 29 (12 boys)], IN (n = 34 (20 boys)), CS (n = 25 (16 boys)) Intervention group increased one unit of sports activities for 3 years 0 No difference among groups
Blizzard LeBlanc 2017 [26] n = 11 OB (6 boys) Canada 15–16 y-o. Acute bouts of exercise: Aerobic: 45 min at 60% HRR + In all subjects
Resistance: 45 min at 60–65% 1RM 12–15 reps 0 In all subjects
Palacios-González 2015 [6] n = 85 (40 boys) Mexico 8–10 y-o. NW (n = 25), OW (n = 23), OB (n = 37). 5-min warm-up and 25-min aerobic activity at 75% HRMax, 8 months, 5 days/week In all subjects
Blüher 2014 [27] n = 65 Germany OW/OB (35 boys) 7–18 y-o. 39 session over 1 year of 150 min/week of combined endurance and resistance exercise plus diet counseling + In all subjects
Reinehr 2015 [10] n = 60 Germany 10-15 y-o NW (n = 20 (10 boys)), OB (n = 40 (20 boys)). Exercise sessions once per week plus nutrition education for 4–6 weeks 0 In OB children who lost weight
+ In OB children who did not lose weight
Singhal 2014 [12] n = 85 women (81 Caucasian and Asian, 11 mixed-race, 5 Black) 14–21 y-o. AA (n = 38), EA (n = 24), NA (n = 23). No intervention In AA
0 In EA and NA

AA (amenorrheic athletes), CO (Control), CS (Competitive sports), DBP (Dystolic Blood Pressure), EA (eumenorrheic athletes), HRmax (maximum heart rate), HRR (heart rate reserve), IN (Intervention), Ir (irisin), NA (non-athletes), NW (normal weight), OB (obese), OGTT (oral glucose tolerance test), OW (overweight), RM (repetition maximum), UW (underweight) WC (waist circumference), + (positive correlation), − (negative correlation), 0 (no correlation).