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Mechanisms of the miR-23a~27a~24-2 cluster in regulating bovine adipocyte adipogenesis. The miR-23a~27a~24-2 cluster represses adipogenic differentiation of bovine preadipocytes. This inhibitory effect is achieved through a balanced regulation via targeting two types of genes with anti-adipogenic effects (DCN, G6PD, and LPL) and pro-adipogenic effects (GPAM, DGAT2, and FGF11), which finally leads to the miR-23a~27a~24-2 cluster-mediated repression of adipogenesis.
