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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Plot of RMSD vs. time graph for TAK-285 (red), 1a (gray) and 1d (blue). Compound 1a shown to be fluctuating around 0.5 Å, while compounds 1d and TAK-285 were fluctuating around 1.4 and 1.0 Å.