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Cytotoxicity of CRY and the combination of SPC/CRY ULV (1:0.5 mol/mol) in HepG2 cells after 24 h incubation. § p < 0.001 vs. CRY, denotes a statistically significant reduction respect to CRY cytotoxicity (ANOVA + multiple Dunnett’s comparison post-test). A cell viability lower than 70% respect to control (i.e., vehicle-treated cells) was considered as cytotoxic [26].
