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. 2018 Nov 22;23(12):3056. doi: 10.3390/molecules23123056

Figure 5.

Figure 5

The effect of SPB on NLRP3 inflammasome. The NLRP3 inflammasome pathway was explored in MAC-T cells using Western blot analysis. β-actin was used as a reference control. (A) The expression levels of NOD-like receptor protein 3 (NLRP3), apoptosis-associated speck-like protein containing CARD (ASC), caspase-1, and interleukin 1 beta (IL-1β) proteins; (B) The quantification histogram of NLRP3 protein expression normalized by β-actin; (C) The quantification histogram of ASC protein expression normalized by β-actin; (D) The quantification histogram of caspase-1 protein expression normalized by β-actin; and (E) The quantification histogram of IL-1β protein expression normalized by β-actin. The values presented are the means ± SE of three independent experiments. # p < 0.05 vs. control group; ** p < 0.01 vs. LTA group.