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. 2018 Dec 14;23(12):3318. doi: 10.3390/molecules23123318

Figure 6.

Figure 6

OPCs increased the uptake of BB in Caco-2 Cells. Caco-2 intestinal cells were treated with 25 μM of BB and BB with OPCs at 108 mg/L for different time (a) or BB with OPCs at 54 mg/L or 108 mg/L for 2 h (b). Verapamil (100 μM) was used as positive control, cells were harvested for determination of the uptake of BB. Quantities of BB in the cells were determined by LC–MS/MS. Data are presented as mean ± SEM of three independent experiments. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control (BB alone), # p < 0.05 108 mg/L of OPCs vs. verapamil.