BB |
Berberine |
OPCs |
Oligomeric proanthocyanidins |
SD mice |
Sprague Dawley mice |
LC–MS/MS |
Liquid chromatography–tandem mass spectrometry |
P-gp |
P-glycoprotein |
R123 |
Rhodamine-123 |
DM |
Diabetes mellitus |
T2DM |
Type 2 diabetes mellitus |
TCM |
Traditional Chinese medicine |
JTW |
Jiaotaiwan |
ACC |
Acetyl coenzyme A carboxylase |
AMPK |
AMP-activated protein kinase |
GLUT4 |
Glucose transporter 4 |
FBG |
Fasting blood glucose |
OGTT |
Oral glucose tolerance test |
IPTT |
Intraperitoneal insulin tolerance test |
TG |
Total triglyceride |
TC |
Total cholesterol |
ALT |
Alanine transaminase |
AST |
Aspartate transaminase |
AUC |
Area under the curve |
MTT |
Methylthiazolyldiphenyl-tetrazolium bromide |
DMEM |
Dulbecco’s modified Eagle medium |
HBSS |
Hank’s balanced salt solution |
HPLC |
High-performance liquid chromatography |
UPLC |
Ultrahigh performance liquid chromatograph |
ESI |
Electrospray ionization |
THP |
Tetrahydropalmatine |
TL |
Tube lens voltage |
CE |
Collision energies |
DP |
Declustering potential |
CEP |
Cell exit potential |
BL |
Basolateral |
AP |
Apical |
ACTB |
β-Actin |
BCA |
Bicinchoninic acid |