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. 2018 Dec 12;19(12):4016. doi: 10.3390/ijms19124016

Figure 2.

Figure 2

Effect of 50 and 100 mg/kg doses of I. asarifolia (IA) aqueous extract and 250 mg/kg sulfasalazine (SSZ) on the gene expression of c-Jun N-terminal kinases 1 (JNK1) (a), Nuclear factor kappa β (NK-κβ-p65) (b) and Activator of transcription 3 (STAT3) (c) in colonic tissue of the experimental trial of acute colitis induced by 2,4-dinitrobenzene sulfonic acid (DNBS) in rats. H, Healthy group; DNBS, DNBS group; SSZ, sulfasalazine group; and 50 and 100 mg/kg doses of the IA group. Data are expressed as mean ± SEM, (n = 8). Statistical differences * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 of treatments vs. DNBS control were presented.