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. 2018 Dec 7;23(12):3241. doi: 10.3390/molecules23123241

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Influence of cinnamaldehyde-related compounds on LPS-primed TNF-α, IL-1β, NOD-like receptor protein 3 (NLRP3), caspase-1, adaptor proteins- apoptosis-associated speck-like containing CARD (ASC) and P2X7 receptor (P2X7R) mRNA expressions. The macrophages were pretreated with 100 μM cinnamaldehyde-related compounds for 30 min and then treated with LPS. The mRNA levels were detected by RT-qPCR. Data are expressed as the mean ± SD and different superscript letters represent statistically differences (p < 0.05).