Table 2.
Viability of Candida albicans in swabs from vaginal rats inoculated with fluconazole loaded PECs based vaginal inserts (F17) in comparison to unloaded insert and fluconazole solution.
| Time (day) | Control | Unloaded Insert | Fluconazole Loaded PEC Based Insert | Fluconazole Solution |
|---|---|---|---|---|
| T0 | 3.19 ± 3.03 | 2.8 ± 2.7 | 3.1 ± 2.9 | 2.79 ± 2.49 |
| T2 | 2.97 ± 2.71 | 2.49 ± 2.35 | 3.08 ± 2.8 | 2.74 ± 2.58 |
| T5 | 3.03 ± 3.17 | 2.19 ± 2.32 | 2.38 ± 2.2 | 2.99 ± 3.012 |
| T7 | 2.5 ± 2.12 | 2.71 ± 2.85 | - | 2.93 ± 2.75 |
| T21 | 1.87 ± 1.7 | 2.21 ± 2.83 | - | 2.62 ± 2.81 |
Results represent microbial concentration (log CFU ± SD) (n = 6). PEC: Polyelectrolyte complex; control: untreated group.